News

News from The American Academy of Ophthalmology

• Some Patients Require Vitrectomy Even After Successful Pneumatic Retinopexy
  An IRIS Registry study found that nearly 1 in 10 patients required additional vitrectomy surgery after pneumatic retinopexy, often for reasons other than failed retinal detachment repair.
• Military Members May Face Elevated Risk of Mental Health Issues After Enucleation
  An analysis of US military personnel found that individuals who underwent globe removal after traumatic injury had a heightened risk of developing new behavioral health issues, including suicide and anxiety.
• Event-Based Analyses of OCT Parameters Can Effectively Detect Glaucoma Progression Early
  Event-based and trend-based analyses of 2 optical coherence tomography (OCT) parameters were compared to see which method could more effectively detect glaucoma progression.
• Weekly Journal Update — June 25, 2025
  GLP-1 RA use may lower risk of dry AMD, advantages of a VR perimetry device over the HFA, myasthenia gravis symptoms worsen during the day, features and outcomes of Coats disease, PVCA and scleral curvature changes in high myopia.
• Enucleation Without Conjunctival Closure May Be a Viable Surgical Option
  A retrospective chart review evaluated outcomes following enucleation with closure of the Tenon layer only without conjunctival closure.
• Sleep Apnea in Cornea Donors May Negatively Affect Endothelial Cell Density
  A retrospective evaluation of eye bank data noted significantly lower endothelial cell density in corneas from donors with a history of sleep apnea than in donors without reported sleep apnea.
• Real-World Data Suggest High Disease Burden and Progression Rates in AMD
  A large database study found that most eyes with geographic atrophy lost significant visual acuity within 3 years of presentation, with one-fifth developing neovascular AMD.
• Study Provides Insights Into Antibody-Drug Conjugate (ADC)–Induced Corneal Toxicity
  A small case series uncovers a possible mechanism behind the corneal adverse events commonly seen with belantamab mafodotin treatment for multiple myeloma.
• Autologous Stem Cell Transplantation in the Treatment of Vitreoretinal Lymphoma
  A national case series in France evaluated the treatment efficacy of autologous stem cell transplantation with chemotherapy for patients with isolated vitreoretinal lymphoma.
• Weekly Journal Update — June 18, 2025
  Cost of digital devices for treating amblyopia, retinal thinning patterns in glaucomatous eyes with myopia, endophthalmitis risk after microincision vitrectomy, accuracy of Barrett True vs Barrett Universal II, ocular side effects of MEK inhibitor treatment in children.