News

News from The American Academy of Ophthalmology

• Mycophenolate may be superior to other immunomodulators for treating OcMMP
  Patients with ocular mucous membrane pemphigoid (OcMMP) may benefit most from mycophenolate or a mycophenolate–rituximab combination treatment.
• Amsler grid may not be as reliable as once thought for self-monitoring AMD
  Despite ease of use, the Amsler grid may not have adequate sensitivity or specificity to make it a reliable at-home tool for monitoring the progression of AMD.
• Week in review: Monitoring Alzheimer's with retinal images, smoking and myopia, cataract surgery follow-up care
  Changes in retinal vascular tissue could point to dementia, smoking in families increases the risk of myopia in their children, and patients prefer same-day postsurgical care to next-day care.
• Antidrug antibodies in NIU are seen with adalimumab but not infliximab
  Tumor necrosis factor-alpha inhibitors adalimumab and infliximab are common therapies for noninfectious uveitis (NIU), but the presence of antidrug antibodies could result in lower circulating drug levels.
• Ultrathin DSAEK and DMEK appear nearly equivalent in most post-op parameters
  Ultrathin Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) are similarly successful, but one may yield better BCVA.
• Study suggests ocular surface protective effects of repeated anti-VEGF injections
  Undergoing multiple intravitreal injections for age-related macular degeneration may have a positive impact on dry eye disease–related symptoms.
• Tebentafusp may offer a survival benefit for patients with uveal melanoma
  Tebentafusp appears to promote better overall survival than combined immune checkpoint blockage for certain patients with metastatic uveal melanoma.
• Week in review: Firearms-related ocular injuries, AMD and heart disease, new dry eye treatment
  Rates of advanced trauma care for firearms-related ocular injuries vary by age and race, visual disabilities increase the risk of cardiovascular disease in patients with AMD, and MIEBO, a new treatment for dry eye disease, is approved.
• Current smoking status means more likelihood of surgery in thyroid eye disease
  Investigators used data from the IRIS Registry to assess whether smoking status influenced the need for surgical interventions for thyroid eye disease.
• Partial-orbit radiotherapy is a potential treatment option for orbital MALToma
  Partial-orbit radiation may provide effective treatment for orbital mucosa-associated lymphoid tissue lymphoma (MALToma) without the high doses of radiation seen with other radiotherapy technologies.