News

News from The American Academy of Ophthalmology

• Weekly Journal Update — April 29, 2026
  Risk of AMD with GLP-1 RA use vs insulin, nonvalved glaucoma drainage for uveitic glaucoma, biomarkers associated with progression to late AMD, structural brain abnormalities in form-deprivation amblyopia, predicting time to vision loss in GA.
• Fibrin Glue Might Offer Advantages Over Sutures in Primary Pterygium Surgery
  When compared with the use of sutures for securing a conjunctival autograft, fibrin glue appears to modestly reduce the risk of pterygium recurrence and shorten operating time.
• Surgical Indication Appears to Influence the Outcomes of Penetrating Keratoplasty
  Analysis of outcomes after penetrating keratoplasty (PK) found the indication for surgery may be a predictor of graft survival, visual outcomes, and complication rates, with trauma or perforation having worse outcomes and corneal ectasia faring best.
• Early, Aggressive Treatment Is Likely Necessary for Potential Visual Recovery from CRAO
  Available evidence on central retinal artery occlusion (CRAO) shows conservative management to be rarely beneficial and potentially harmful, but prompt thrombolytic intervention provides the best chance of some visual recovery.
• Retinal Vascular Occlusion May Be Associated With Increased Risk of Dementia
  A large cohort study found that patients with retinal vascular occlusion, including arterial and venous subtypes, may face elevated risks of Alzheimer's disease, vascular dementia, and all-cause dementia.
• An Increase in US Syphilis Cases Means a Corresponding Increase in Syphilitic Uveitis
  The increased prevalence in syphilitic uveitis in the United States during the past decade reflects the general increase in syphilis infections overall.
• Diagnostic Biopsy May Be a Primary Surgical Option for Pediatric Orbital Rhabdomyosarcoma
  A study found that in pediatric patients with primary orbital rhabdomyosarcoma, biopsy-only surgery was noninferior to debulking surgery for preserving the eye.
• Weekly Journal Update — April 22, 2026
  15-year rate of OAG, PPV and ILM flaps for optic disc pit maculopathy, effects of melatonin on sleep in patients with glaucoma, ocular traumas from mass pager/radio explosions, PAC risk in a BEST1-associated retinopathy.
• Modifiable Cardiovascular Factors Do Not Appear to Affect Vision Loss in NAION
  An analysis of data from the large NAION QRK207 treatment study found no association between modifiable cardiovascular risk factors (e.g., hypertension, obesity) and progression of vision loss.
• Deep Learning Model Detects Macular Diseases Across Multiple OCT Imaging Systems
  A model trained on macular scans from the Spectralis OCT system was able to reliably identify macular diseases using novel scans taken with either the Spectralic or Cirrus OCT systems.