News

News from The American Academy of Ophthalmology

• In Some Patients With TED, Teprotumumab May Reduce Orbital Muscle and Fat Volume
  Patients with thyroid eye disease (TED) who have high pre-treatment proptosis and orbital muscle volume may benefit more from teprotumumab treatment than other patients with TED.
• Trend Toward Globe-Sparing Treatments for Retinoblastoma in the United States
  Rates of enucleation for retinoblastoma appear to have decreased in the US from 2004 to 2016, though these trends were not equally distributed among all patient groups.
• Week in Review: Pregnancy and Severe Diabetic Retinopathy, Role of Visual Defects in Auto Accidents
  Women with type 1 diabetes may not incur an additional risk of severe diabetic retinopathy either during or after pregnancy, and people with visual defects could be more likely to have motor vehicle accidents.
• A Single Enlarged Extraocular Muscle Could Be a Sign of Something More Serious
  A retrospective study evaluated clinical presentations, imaging patterns, and muscle biopsies in a cohort of patients with a single enlarged extraocular muscle.
• Common Acne Medications May Result in Idiopathic Intracranial Hypertension
  Approximately 8% of reported idiopathic intracranial hypertension cases may be related to the use of tetracyclines and vitamin A derivatives, common components in acne and anti-aging products.
• Weekly Journal Update — August 27, 2025
  Glaucoma genetic risk scores and VF patterns, ellipsoid zone loss and early AMD progression, AI vs expert graders in detecting referable glaucoma, standard eye dominance test vs visual simulator, AI-generated retinal images.
• There May be Seasonal Variations in Episodes of HLA-B27–Associated Uveitis
  A retrospective review from a tertiary referral center in Auckland, New Zealand, examined seasonal variation in HLA-B27–associated anterior uveitis over a 12-year period.
• ILM Peeling May Improve Surgical Outcomes for Grade C Proliferative Vitreoretinopathy
  Eyes with grade C proliferative vitreoretinopathy had better visual and anatomic results when pars plana vitrectomy involved internal limiting membrane (ILM) peeling.
• Retinal Detachment After Pediatric Cataract Surgery May be More Likely in Some Patients
  Children who undergo cataract surgery may be more prone to developing postsurgical retinal detachment if they have certain risk factors.
• Intravascular Injection of Soft-Tissue Fillers Can Have Severe Visual Consequences
  A comprehensive literature review finds that ocular complications from cosmetic soft-tissue filler injections, though rare, can result in severe and sometimes irreversible vision loss.